BDBM400235 6-((1-(Cyclopropylmethyl)-1H-imidazo[4,5-b]pyrazin-6-yl)amino)-3-methylbenzo[d]oxazol-2(3H)-one::US10016439, 43

SMILES Cn1c2ccc(Nc3cnc4ncn(CC5CC5)c4n3)cc2oc1=O

InChI Key InChIKey=AXGJXKQJTOUROB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400235   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM400235(6-((1-(Cyclopropylmethyl)-1H-imidazo[4,5-b]pyrazin...)
Affinity DataKi:  42nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
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