BDBM4001 1 H-indole-3-alkanamide deriv. 10j::N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide

SMILES O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)NCc2ccccc2)[nH]c2ccccc12)NCc1ccccc1

InChI Key InChIKey=JIEAIEPFEUNUQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4001   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4001(N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 850nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4001(N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 2.90E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed