BDBM4000 1 H-indole-3-alkanamide deriv. 10i::2,2-Dithiobis(N-phenyl-1H-indole-3-propanamide)::N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]propanamide

SMILES O=C(CCc1c(SSc2[nH]c3ccccc3c2CCC(=O)Nc2ccccc2)[nH]c2ccccc12)Nc1ccccc1

InChI Key InChIKey=MGXQRBDSSCCBIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4000   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4000(N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4000(N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 4.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4000(N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 850nMAssay Description:Inhibition of EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed