BDBM399808 N-(1-(7-(3-chloro-4-(pyrrolidin-1- yl)benzyl)-2,7-diazaspiro[4.4]nonane-2- carbonyl)-1H-pyrazol-4-yl)-N- methylacetamide::US10323038, Example 67

SMILES CN(C(C)=O)c1cnn(c1)C(=O)N1CCC2(CCN(Cc3ccc(N4CCCC4)c(Cl)c3)C2)C1

InChI Key InChIKey=AJORBADDMGCBPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 399808   

TargetFatty-acid amide hydrolase 1(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399808(US10323038, Example 67 | N-(1-(7-(3-chloro-4-(pyrr...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399808(US10323038, Example 67 | N-(1-(7-(3-chloro-4-(pyrr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent