BDBM399806 N-methyl-N-(1-(7-(3- (trifluoromethyl)benzyl)-2,7- diazaspiro[4.4]nonane-2-carbonyl)-1H- pyrazol-4-yl)acetamide (single enantiomer)::US10323038, Example 65::US10323038, Example 66

SMILES CN(C(C)=O)c1cnn(c1)C(=O)N1CCC2(CCN(Cc3cccc(c3)C(F)(F)F)C2)C1

InChI Key InChIKey=LISJXCKVLXLUID-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 399806   

TargetFatty-acid amide hydrolase 1(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399806(US10323038, Example 65 | N-methyl-N-(1-(7-(3- (tri...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399806(US10323038, Example 65 | N-methyl-N-(1-(7-(3- (tri...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399806(US10323038, Example 65 | N-methyl-N-(1-(7-(3- (tri...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Mouse)
Abide Therapeutics

US Patent
LigandPNGBDBM399806(US10323038, Example 65 | N-methyl-N-(1-(7-(3- (tri...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent