BDBM398519 US10323020, Example 13::US10323020, Example 14::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2,6-dimethylmorpholin-4-yl)pyrimidin-5-yl]methanone (Cis Isomer)

SMILES CC1CN(CC(C)O1)c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1

InChI Key InChIKey=BMYFKCKNBYKSDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 398519   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM398519(US10323020, Example 13 | US10323020, Example 14 | ...)
Affinity DataIC50: 47nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM398519(US10323020, Example 13 | US10323020, Example 14 | ...)
Affinity DataIC50: 24nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent