BDBM398513 (rac)-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(1-hydroxybutan-2-yl)amino]pyrimidin-5-yl}methanone::US10323020, Example 7

SMILES CCC(CO)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1

InChI Key InChIKey=JUDQBCCVUKHJJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398513   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM398513(US10323020, Example 7 | (rac)-[4-(3,4-Dihydroisoqu...)
Affinity DataIC50: 68nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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