BDBM3985 2,2 -Dithiobis(7-methyl-1H-indole-3-propanoic acid)::3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]disulfanyl}-7-methyl-1H-indol-3-yl)propanoic acid::dithiobis(1H-indole-3-alkanoic acid) deriv. 33

SMILES Cc1cccc2c(CCC(O)=O)c(SSc3[nH]c4c(C)cccc4c3CCC(O)=O)[nH]c12

InChI Key InChIKey=VSGQCGRYAAEEEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3985   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3985(3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]d...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3985(3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed