BDBM3979 2,2 -Dithiobis(1H-indole-3-propanoic acid)::3-(2-{[3-(2-carboxyethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)propanoic acid::CHEMBL79704::dithiobis(1H-indole-3-alkanoic acid) deriv. 27

SMILES OC(=O)CCc1c(SSc2[nH]c3ccccc3c2CCC(O)=O)[nH]c2ccccc12

InChI Key InChIKey=WKVZBEWEEYDDMO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3979   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3979(2,2 -Dithiobis(1H-indole-3-propanoic acid) | 3-(2-...)
Affinity DataIC50: 4.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3979(2,2 -Dithiobis(1H-indole-3-propanoic acid) | 3-(2-...)
Affinity DataIC50: 4.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM3979(2,2 -Dithiobis(1H-indole-3-propanoic acid) | 3-(2-...)
Affinity DataIC50: 5.10E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM3979(2,2 -Dithiobis(1H-indole-3-propanoic acid) | 3-(2-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentration of the against pp60v-src tyrosine kinase obtained from v-src baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3979(2,2 -Dithiobis(1H-indole-3-propanoic acid) | 3-(2-...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory concentration compound against EFGR tyrosine kinase obtained from plasma membrane vesicles from cultured A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed