BDBM39756 1H-Pyrazole-3-carboxylic acid [tert-butylcarbamoyl-(4-fluoro-phenyl)-methyl]-(4-methoxy-phenyl)-amide::MLS000121706::N-[2-(tert-butylamino)-1-(4-fluorophenyl)-2-keto-ethyl]-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide::N-[2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxidanylidene-ethyl]-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide::N-[2-(tert-butylamino)-1-(4-fluorophenyl)-2-oxoethyl]-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide::SMR000119164::cid_3221278

SMILES Cc3c2CN(C(=O)CCOC[C@H](C)Oc1cn[nH]c(=O)c1C(F)(F)F)CCn2c4ncc(C(F)(F)F)cc34

InChI Key InChIKey=CQHSJDJJSJOSIN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 39756   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 39756BDBM39756(US20260098039, Compound I)
Affinity DataIC50: 1.58nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent