BDBM397103 2-{5-methyl-2-[5-{(3-(2H-1,2,3- triazol-2-yl)pyridin-2-yl]carbonyl} hexahydropyrrolo[3,4-c]pyrrol-2(1H)- yl]-1,3-oxazol-4-yl}propan-2-ol::US9987255, 17

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1ncccc1-n1nccn1

InChI Key InChIKey=JKOKHACZNAWKCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397103   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397103(US9987255, 17 | 2-{5-methyl-2-[5-{(3-(2H-1,2,3- tr...)
Affinity DataIC50: 84nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397103(US9987255, 17 | 2-{5-methyl-2-[5-{(3-(2H-1,2,3- tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent