BDBM397100 2-{5-methyl-2-[5-{(2-(1H- pyrazol-1- yl)phenyl]carbonyl}hexahydropyrrolo [3,4-c]pyrrol-2(1H)-yl]-1,3- oxazol-4-yl}propan-2-ol::US9987255, 14

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1ccccc1-n1cccn1

InChI Key InChIKey=LRCUKRPBDJODPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397100   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397100(US9987255, 14 | 2-{5-methyl-2-[5-{(2-(1H- pyrazol-...)
Affinity DataIC50: 72nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397100(US9987255, 14 | 2-{5-methyl-2-[5-{(2-(1H- pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent