BDBM397091 2-(5-methyl-2-{5-[(3- phenylpyridin-2-yl) carbonyl]hexahydropyrrolo[3,4-c] pyrrol-2(1H)-yl}-1,3-oxazol-4-yl) propan-2-ol::US9987255, 5

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1ncccc1-c1ccccc1

InChI Key InChIKey=KGGYCMXOMZBSJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397091   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397091(US9987255, 5 | 2-(5-methyl-2-{5-[(3- phenylpyridin...)
Affinity DataIC50: 583nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
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Date in BDB:
4/25/2020
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397091(US9987255, 5 | 2-(5-methyl-2-{5-[(3- phenylpyridin...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent