BDBM397085 (2-(2H-1,2,3-triazol-2-yl)phenyl)(5-(4-(2-hydroxypropan-2-yl)-5-methyloxazol-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanon::US9987255, 1

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=BJZWFLCAVRTLBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397085   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397085(US9987255, 1 | (2-(2H-1,2,3-triazol-2-yl)phenyl)(5...)
Affinity DataIC50: 27nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397085(US9987255, 1 | (2-(2H-1,2,3-triazol-2-yl)phenyl)(5...)
Affinity DataIC50: 6.88E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent