BDBM396791 5-(6'-(trifluoromethyl)-[2,2'-bipyridin]-3- yl)pyrazolo[1,5-a]pyrimidine::US9981944, Example 136

SMILES FC(F)(F)c1cccc(n1)-c1ncccc1-c1ccn2nccc2n1

InChI Key InChIKey=WOWFGKMSMRXUJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396791   

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396791(US9981944, Example 136 | 5-(6'-(trifluoromethyl)-[...)
Affinity DataIC50: 15nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396791(US9981944, Example 136 | 5-(6'-(trifluoromethyl)-[...)
Affinity DataIC50: 1.50E+4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent