BDBM396676 6-(4'-fluoro-[2,2'-bipyridin]-3- yl)imidazo[1,2-a]pyridine-3-carboxamide::US9981944, Example 22

SMILES NC(=O)c1cnc2ccc(cn12)-c1cccnc1-c1cc(F)ccn1

InChI Key InChIKey=FGDDJMSOVWYXMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396676   

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396676(US9981944, Example 22 | 6-(4'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396676(US9981944, Example 22 | 6-(4'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 1.27E+4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent