BDBM396673 6-(5'-fluoro-6'-methyl-[2,2'-bipyridin]-3- yl)imidazo[1,2-a]pyridine-3-carboxamide::US9981944, Example 19

SMILES Cc1nc(ccc1F)-c1ncccc1-c1ccc2ncc(C(N)=O)n2c1

InChI Key InChIKey=GAMFQISAYKUQHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396673   

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396673(US9981944, Example 19 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396673(US9981944, Example 19 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 9.62E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent