BDBM396590 3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetidine::US9981909, Example 215

SMILES CC1(CNC1)Oc1cc(Br)ccc1OCCc1ccccc1

InChI Key InChIKey=BJCYJONYVDPPGZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 396590   

Target5-hydroxytryptamine receptor 2A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(US9981909, Example 215 | 3-(5-Bromo-2-phenethyloxy...)
Affinity DataKi:  6nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
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Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(US9981909, Example 215 | 3-(5-Bromo-2-phenethyloxy...)
Affinity DataKi:  11nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(US9981909, Example 215 | 3-(5-Bromo-2-phenethyloxy...)
Affinity DataKi:  17nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(US9981909, Example 215 | 3-(5-Bromo-2-phenethyloxy...)
Affinity DataKi:  26nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(US9981909, Example 215 | 3-(5-Bromo-2-phenethyloxy...)
Affinity DataKi:  44nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent