BDBM396468 (R)-3-[4-Chloro-2-(3-chloro-benzyloxy)-phenoxy]-1-methyl-pyrrolidine::US9981909, Example 93

SMILES CN1CC[C@H](C1)Oc1ccc(Cl)cc1OCc1cccc(Cl)c1

InChI Key InChIKey=HPVJUDGUFWLJAL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 396468   

Target5-hydroxytryptamine receptor 2A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396468(US9981909, Example 93 | (R)-3-[4-Chloro-2-(3-chlor...)
Affinity DataKi:  3nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396468(US9981909, Example 93 | (R)-3-[4-Chloro-2-(3-chlor...)
Affinity DataKi:  13nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396468(US9981909, Example 93 | (R)-3-[4-Chloro-2-(3-chlor...)
Affinity DataKi:  51nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396468(US9981909, Example 93 | (R)-3-[4-Chloro-2-(3-chlor...)
Affinity DataKi:  140nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent