BDBM396429 3-[5-Chloro-2-(5-trifluoromethyl-furan-2-ylmethoxy)-phenoxy]-azetidine::US9981909, Example 54

SMILES FC(F)(F)c1ccc(COc2ccc(Cl)cc2OC2CNC2)o1

InChI Key InChIKey=REZCRIHCCMBVRE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 396429   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396429(US9981909, Example 54 | 3-[5-Chloro-2-(5-trifluoro...)
Affinity DataKi:  6nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396429(US9981909, Example 54 | 3-[5-Chloro-2-(5-trifluoro...)
Affinity DataKi:  28nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396429(US9981909, Example 54 | 3-[5-Chloro-2-(5-trifluoro...)
Affinity DataKi:  77nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent