BDBM396417 3-[5-Chloro-2-(4-trifluoromethoxy-benzyloxy)-phenoxy]-azetidine::US9981909, Example 42

SMILES FC(F)(F)Oc1ccc(COc2ccc(Cl)cc2OC2CNC2)cc1

InChI Key InChIKey=WBTFCOFOKWHTQM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396417   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396417BDBM396417(US9981909, Example 42 | 3-[5-Chloro-2-(4-trifluoro...)
Affinity DataKi:  35nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396417BDBM396417(US9981909, Example 42 | 3-[5-Chloro-2-(4-trifluoro...)
Affinity DataKi:  578nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent