BDBM396409 3-[2-(Azetidin-3-yloxy)-4-chloro-phenoxymethyl]-benzonitrile::US9981909, Example 34

SMILES Clc1ccc(OCc2cccc(c2)C#N)c(OC2CNC2)c1

InChI Key InChIKey=XHABIFOGQCIGRN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396409   

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396409(US9981909, Example 34 | 3-[2-(Azetidin-3-yloxy)-4-...)
Affinity DataKi:  1nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396409(US9981909, Example 34 | 3-[2-(Azetidin-3-yloxy)-4-...)
Affinity DataKi:  29nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent