BDBM396385 3-[5-Bromo-2-(5-trifluoromethyl-furan-2-ylmethoxy)-phenoxy]-azetidine::US9981909, Example 10

SMILES FC(F)(F)c1ccc(COc2ccc(Br)cc2OC2CNC2)o1

InChI Key InChIKey=PFMYETFUEGGSNC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 396385   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396385(US9981909, Example 10 | 3-[5-Bromo-2-(5-trifluorom...)
Affinity DataKi:  7nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396385(US9981909, Example 10 | 3-[5-Bromo-2-(5-trifluorom...)
Affinity DataKi:  39nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396385(US9981909, Example 10 | 3-[5-Bromo-2-(5-trifluorom...)
Affinity DataKi:  50nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent