BDBM396361 US9980929, Example 63

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)C(Cc1ccccc1)Oc1cc(F)cc(F)c1)c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=QVEMIKYQYAQAKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396361   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM396361(US9980929, Example 63)
Affinity DataIC50: 4.53nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent