BDBM396324 US9980929, Example 22

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)\C=C\c1cc(Cl)cc(Cl)c1)C(=O)C(F)(F)F

InChI Key InChIKey=BUVXBYWPDUCXHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396324   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM396324(US9980929, Example 22)
Affinity DataIC50: 60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent