BDBM396089 US10308660, Example 191

SMILES Cn1c(nc(N)c(-c2ccccc2)c1=O)N1CCC2(CCC[C@H]2N)CC1

InChI Key InChIKey=TUCRSFSTNQCBPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396089   

LigandPNGBDBM396089(US10308660, Example 191)
Affinity DataIC50: 27nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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