BDBM396038 US10308660, Example 140::US12053470, Compound 36

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc(N)c(-c2ccccc2)c(=O)n1C

InChI Key InChIKey=LNQYLYAZNKGMBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396038   

LigandPNGBDBM396038(US10308660, Example 140 | US12053470, Compound 36)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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LigandPNGBDBM396038(US10308660, Example 140 | US12053470, Compound 36)
Affinity DataIC50: 25nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
Go to US Patent