BDBM396029 US10308660, Example 131

SMILES CC(C)c1ccc(cc1)-c1c(N)nc(N2CCC3(CO[C@@H](C)[C@H]3N)CC2)n(C)c1=O

InChI Key InChIKey=YSASWDDSHGKHFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396029   

LigandPNGBDBM396029(US10308660, Example 131)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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