BDBM396023 US10308660, Example 124

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc(N)c(-c2ccc(C)c(Cl)c2)c(=O)n1C

InChI Key InChIKey=IJJXFRROUFAAJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396023   

LigandPNGBDBM396023(US10308660, Example 124)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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