BDBM395788 US10308654, Example 16

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N4CCC4)n(N4CCCCC4)c3n2)nc1

InChI Key InChIKey=DEJRNFXBCMYLTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395788   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Changzhou Longthera Pharmaceuticals

US Patent
LigandPNGBDBM395788(US10308654, Example 16)
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Changzhou Longthera Pharmaceuticals

US Patent
LigandPNGBDBM395788(US10308654, Example 16)
Affinity DataIC50: 550nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent