BDBM395782 2-(5-(9-(2-(Difluoromethoxy)phenyl)-7,9-dihydro-6H-pyrano[4′,3′:4,5]imidazo[1,2-b]pyridazin-2-yl)pyrimidin-2-yl)propan-2-ol::US10308652, Example 63

SMILES CC(C)(O)c1ncc(cn1)-c1ccc2nc3CCOC(c3n2n1)c1ccccc1OC(F)F

InChI Key InChIKey=ZDJURXUJJAGERM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395782   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM395782(2-(5-(9-(2-(Difluoromethoxy)phenyl)-7,9-dihydro-6H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent