BDBM395779 9-(2-(Difluoromethoxy)phenyl)-2-(4-(2-hydroxypropan-2-yl)phenyl)-6-(pyridin-4-yl)-6,9-dihydro-7H-pyrano[4′,3′:4,5]imidazo[1,2-b]pyridazin-6-ol::US10308652, Example 60

SMILES CC(C)(O)c1ccc(cc1)-c1ccc2nc3c(C(OCC3(O)c3ccncc3)c3ccccc3OC(F)F)n2n1

InChI Key InChIKey=OLQONTXLRKBPMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395779   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM395779(9-(2-(Difluoromethoxy)phenyl)-2-(4-(2-hydroxypropa...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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