BDBM395708 4-amino-N-((1S,3R)-3-(5-cyclopropyl-4-(1H-indol-3-yl)pyrimidin-2-ylamino)cyclohexyl)benzamide::US10308648, Compound 103::US10865206, Compound 103

SMILES Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(C2CC2)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=OMPFSFIPOUSAFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395708   

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395708(US10308648, Compound 103 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395708(US10308648, Compound 103 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
Go to US Patent