BDBM395446 3-chloro-6-((4-(((3-chloro-6-fluoro-1H-indol-5- yl)methyl)carbamoyl)pyridin-2- yl)methyl)quinoline-8-carboxamide::US10308637, Example 59

SMILES Cc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccnc(Cc2cc(C(N)=O)c3ncc(Cl)cc3c2)c1

InChI Key InChIKey=HPVYEXUZBLVVTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395446   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM395446(3-chloro-6-((4-(((3-chloro-6-fluoro-1H-indol-5- yl...)
Affinity DataIC50: 100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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