BDBM395388 US10308636, Example 23-1

SMILES COC[C@@]1(CC[C@@H](CC1)Oc1ccc(cc1)-c1ccc(cn1)-c1nc(C)c([nH]1)C(F)(F)F)C(O)=O

InChI Key InChIKey=MBULWKHZXPBIMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395388   

TargetDiacylglycerol O-acyltransferase 1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395388(US10308636, Example 23-1)
Affinity DataIC50: 3.30nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent