BDBM395355 US10308636, Example 43-1

SMILES Cc1cccc(OCC2CCN(CC2)c2ccc(cn2)-c2nc(cn2COCC[Si](C)(C)C)C(F)(F)F)c1

InChI Key InChIKey=HCZWWTGJZLFPBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395355   

TargetDiacylglycerol O-acyltransferase 1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395355(US10308636, Example 43-1)
Affinity DataIC50: 8.5nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent