BDBM395339 (S)-1-((7-chloro-2-(2′-chloro-3′-(5-(((2-hydroxyethyl)amino)methyl)picolinamido)-2-methyl-[1,1′-biphenyl]-3-yl)benzo[d]oxazol-5-yl)methyl)piperidine-2-carboxylic acid::US10308644, Example 1::US10800768, Example 1::US11339149, Example 1

SMILES Cc1c(cccc1-c1cccc(NC(=O)c2ccc(CNCCO)cn2)c1Cl)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)cc(Cl)c2o1

InChI Key InChIKey=HRCYHLZZZCKHJI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 395339   

LigandPNGBDBM395339((S)-1-((7-chloro-2-(2′-chloro-3′-(5-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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LigandPNGBDBM395339((S)-1-((7-chloro-2-(2′-chloro-3′-(5-((...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM395339((S)-1-((7-chloro-2-(2′-chloro-3′-(5-((...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM395339((S)-1-((7-chloro-2-(2′-chloro-3′-(5-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
Go to US Patent