BDBM395324 US10308636, Example 3-7

SMILES Cc1cc(OCC2(CC2)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)-c2ccccc2OC(F)(F)F)c(F)c1

InChI Key InChIKey=VJUAXCILDHTBPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395324   

TargetDiacylglycerol O-acyltransferase 1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395324(US10308636, Example 3-7)
Affinity DataIC50: 2.5nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent