BDBM395322 US10308636, Example 2-11

SMILES COc1ccc(cc1)-c1cnc([nH]1)-c1ccc(cc1)-c1cnc(OCC(C)(C)C([O-])=O)cc1C

InChI Key InChIKey=HBFMSQKPDHQASP-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395322   

TargetDiacylglycerol O-acyltransferase 1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395322(US10308636, Example 2-11)
Affinity DataIC50: 3.70nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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