BDBM3953 5-Substituted 1-Phenylbenzimidazole 42::Methyl 5-Methoxy-1-phenylbenzimidazole-6-carboxylate Hydrochloride::methyl 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-carboxylate

SMILES COC(=O)c1cc2n(cnc2cc1OC)-c1ccccc1

InChI Key InChIKey=AIARRPNZZRCXGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3953   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM3953(methyl 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-ca...)
Affinity DataIC50: 870nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM3953(methyl 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-ca...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM3953(methyl 5-methoxy-1-phenyl-1H-1,3-benzodiazole-6-ca...)
Affinity DataIC50: 3.33E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed