BDBM395297 N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide::US10308634, Example 12::US10793545, Example 12::US11992481, Example 12::US12006303, Example 12
SMILES CC(C)(O)c1cc2nn(CCS(C)(=O)=O)cc2cc1NC(=O)c1cccc(n1)C(F)(F)F
InChI Key InChIKey=OQAMEEFUUFJZRS-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 395297
Affinity DataIC50: 10.7nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMAssay Description:The IRAK4-inhibitory activity of the inventive substances was measured in the IRAK4 TR-FRET assay (TR-FRET=Time Resolved Fluorescence Resonance Energ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of N-terminal His6/GST-tagged recombinant human TrkA (443 to 796 residues) expressed in Sf9 cells using biotinylated-polyGlu,Tyr (4:1) cop...More data for this Ligand-Target Pair