BDBM395284 N-{4-[[(4aR,5aR) or (4aS,5aS)]-3-anilino-5a-methyl-4-oxo-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indol-2-yl]pyridin-2-yl}-3-fluoro-4-methoxybenzamide::US10308629, Example 50

SMILES COc1ccc(cc1F)C(=O)Nc1cc(ccn1)-c1[nH]c2C[C@@]3(C)C[C@H]3C(=O)c2c1Nc1ccccc1

InChI Key InChIKey=UKFFINOSEWVIBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395284   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395284(US10308629, Example 50 | N-{4-[[(4aR,5aR) or (4aS,...)
Affinity DataIC50: 13nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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