BDBM395262 (7RS)-2-(2-Aminopyridin-4-yl)-7-methyl-3-(phenylamino)-5,6,7,8-tetrahydrocyclohepta[b]pyrrol-4(1H)-one::US10308629, Example 24

SMILES CC1CCC(=O)c2c(C1)[nH]c(c2Nc1ccccc1)-c1ccnc(N)c1

InChI Key InChIKey=LRAXLMYPRZQTNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395262   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
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US Patent
LigandPNGBDBM395262(US10308629, Example 24 | (7RS)-2-(2-Aminopyridin-4...)
Affinity DataIC50: 25nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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