BDBM395260 3-(Phenylamino)-2-(pyridin-4-yl)-5,6,7,8-tetrahydrocyclohepta[b]pyrrol-4(1H)-one::US10308629, Example 22

SMILES O=C1CCC=Cc2[nH]c(c(Nc3ccccc3)c12)-c1ccncc1

InChI Key InChIKey=GUODEKXDWWIAGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395260   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395260(US10308629, Example 22 | 3-(Phenylamino)-2-(pyridi...)
Affinity DataIC50: 6nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent