BDBM395257 N-4-[(4aR,5aR or 4aS,5aS)-5a-Methyl-4-oxo-3-(phenylamino)-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indol-2-yl]pyridin-2-ylacetamide::US10308629, Example 19

SMILES CC1(CO)CC(=O)C(C(=S)Nc2ccccc2)=C(C1)NCc1ccnc(N)c1

InChI Key InChIKey=BIWFQKGLKYOTER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395257   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395257(US10308629, Example 19 | N-4-[(4aR,5aR or 4aS,5aS)...)
Affinity DataIC50: 8nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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