BDBM395247 1-cyclopropyl-3-4-[rel-(5R,7S)-6,6-Dimethyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-5,7-methanoindol-2-yl]pyridin-2-ylurea::US10308629, Example 9

SMILES CC1(C)[C@@H]2C[C@H]1C(=O)c1c(Nc3ccccc3)c([nH]c21)-c1ccnc(NC(=O)NC2CC2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395247   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395247(US10308629, Example 9 | 1-cyclopropyl-3-4-[rel-(5R...)
Affinity DataIC50: 240nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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