BDBM395245 US10308629, Example 7::methyl 4-[rel-(5R,7S)-6,6-Dimethyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-5,7-methanoindol-2-yl]pyridin-2-ylcarbamate

SMILES COC(=O)Nc1cc(ccn1)-c1[nH]c2[C@H]3C[C@@H](C(=O)c2c1Nc1ccccc1)C3(C)C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395245   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395245(US10308629, Example 7 | methyl 4-[rel-(5R,7S)-6,6-...)
Affinity DataIC50: 68nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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