BDBM395118 3-({2-[(1- phenylcyclobutyl) amino]pyrimidin- 5- yl}carbonyl) benzonitrile::US10308615, Example 129

SMILES O=C(c1cnc(NC2(CCC2)c2ccccc2)nc1)c1cccc(c1)C#N

InChI Key InChIKey=AFWPPKALCNDYNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395118   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395118(US10308615, Example 129 | 3-({2-[(1- phenylcyclobu...)
Affinity DataIC50: 9.90nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395118(US10308615, Example 129 | 3-({2-[(1- phenylcyclobu...)
Affinity DataIC50: 12.4nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent