BDBM395108 US10308615, Example 119::{2-[(pyrimidin-5- ylmethyl)amino] pyrimidin-5-yl}[3- (trifluoromethyl) phenyl]methanone

SMILES FC(F)(F)c1cccc(c1)C(=O)c1cnc(NCc2cncnc2)nc1

InChI Key InChIKey=YXUQMWCGELHLOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395108   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395108(US10308615, Example 119 | {2-[(pyrimidin-5- ylmeth...)
Affinity DataIC50: 11.3nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395108(US10308615, Example 119 | {2-[(pyrimidin-5- ylmeth...)
Affinity DataIC50: 6.10nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent