BDBM395085 US10308615, Example 96::{2-[(4- fluorobenzyl) amino]pyrimidin-5- yl}[3- (methylsulfonyl) phenyl]methanone

SMILES CS(=O)(=O)c1cccc(c1)C(=O)c1cnc(NCc2ccc(F)cc2)nc1

InChI Key InChIKey=AOIAZXAIBOFFCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395085   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395085(US10308615, Example 96 | {2-[(4- fluorobenzyl) ami...)
Affinity DataIC50: 14.2nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395085(US10308615, Example 96 | {2-[(4- fluorobenzyl) ami...)
Affinity DataIC50: 415nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent